MR-guided joint reconstruction of activity and attenuation in brain PET-MR
نویسندگان
چکیده
منابع مشابه
MR-guided joint reconstruction of activity and attenuation in brain PET-MR
With the advent of time-of-flight (TOF) PET scanners, joint maximum-likelihood reconstruction of activity and attenuation (MLAA) maps has recently regained attention for the estimation of PET attenuation maps from emission data. However, the estimated attenuation and activity maps are scaled by unknown scaling factors. We recently demonstrated that in hybrid PET-MR, the scaling issue of this al...
متن کاملMR constrained simultaneous reconstruction of activity and attenuation maps in brain TOF-PET/MR imaging
Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, CH-1211 Geneva, Switzerland The maximum likelihood estimation of attenuation and activity (MLAA) algorithm has been proposed to jointly estimate activity and attenuation from emission data only. Salomon et al employed the MLAA to estimate activity and attenuation from time-offlight PET data with spatial MR prior inf...
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Introduction: Magnetic Resonance (MR) imaging has emerged as a valuable tool in radiation treatment (RT) planning as well as Positron Emission Tomography (PET) imaging owing to its superior soft-tissue contrast. Due to the fact that there is no direct transformation from voxel intensity in MR images into electron density, itchr('39')s crucial to generate a pseudo-CT (Computed Tomography) image ...
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UNLABELLED PET/MR offers potential advantages over PET/CT that are currently under investigation. One of the challenges of PET/MR is attenuation correction, as there is no simple correlation between MR signal intensity and the attenuation of 511-keV photons detected in PET. Currently, dedicated MR sequences are used to segment voxels into categories that are then assigned a predetermined attenu...
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German Cancer Research Center (DKFZ), Heidelberg, Germany Accurate quantification of the activity distribution in positron emission tomography (PET) mandates attenuation correction (AC). Unlike in PET/CT, AC in PET/MR is, however, challenging, since information about the attenuation properties of the patient tissue distribution is not available directly. Standard MR-based AC (MRAC) does not acc...
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ژورنال
عنوان ژورنال: NeuroImage
سال: 2017
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2017.09.006